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Oxidized alginate hydrogels for BMP-2 delivery in long bone defects

Autograft treatment of large bone defects and fracture non-unions is complicated by limited tissue availability and donor site morbidity. Polymeric biomaterials such as alginate hydrogels provide an attractive tissue engineering alternative due to their biocompatibility, injectability, and tunable d...

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Bibliographic Details
Main Authors: Priddy, Lauren B, Chaudhuri, Ovijit, Stevens, Hazel Y, Krishnan, Laxminarayanan, Uhrig, Brent A, Willett, Nick J, Guldberg, Robert E
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160396/
https://ncbi.nlm.nih.gov/pubmed/24954001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.06.015
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