Hydrogel-based Delivery of rhBMP-2 Improves Healing of Large Bone Defects Compared With Autograft

BACKGROUND: Autologous bone grafting remains the gold standard in the treatment of large bone defects but is limited by tissue availability and donor site morbidity. Recombinant human bone morphogenetic protein-2 (rhBMP-2), delivered with a collagen sponge, is clinically used to treat large bone def...

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Pubblicato in:Clin Orthop Relat Res
Autori principali: Krishnan, Laxminarayanan, Priddy, Lauren B., Esancy, Camden, Li, Mon-Tzu Alice, Stevens, Hazel Y., Jiang, Xi, Tran, Lisa, Rowe, David W., Guldberg, Robert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
Soggetti:
Symposium: Research Advances After a Decade of War
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523508/
https://ncbi.nlm.nih.gov/pubmed/25917422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4312-z
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