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Nanoparticle-Assisted Targeted Delivery of Eye-Specific Genes to Eyes Significantly Improves the Vision of Blind Mice In Vivo

[Image: see text] Application of viruses as a carrier, though not safe, to deliver genes to eye tissue was successful. However, a safer, nonviral, biocompatible lipid-based nanoparticle has never been tested to treat blinding eye diseases. We created an artificial virus using a nanoparticle, liposom...

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Bibliografische gegevens
Hoofdauteurs: Rajala, Ammaji, Wang, Yuhong, Zhu, Ye, Ranjo-Bishop, Michelle, Ma, Jian-Xing, Mao, Chuanbin, Rajala, Raju V. S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2014
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160266/
https://ncbi.nlm.nih.gov/pubmed/25115433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl502275s
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