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Role of the Phagocyte in Host-Parasite Interactions XXIV. Aldehyde Generation by the Myeloperoxidase-H(2)O(2)-Chloride Antimicrobial System: a Possible In Vivo Mechanism of Action

Myeloperoxidase (MPO), H(2)O(2), and chloride ions in the presence of bacteria form aldehydes and are bactericidal. The use of heat-inactivated MPO prevented both killing and aldehyde generation. Decarboxylation and deamination of carboxyl and amino group substrates arising from the bacterial surfac...

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Hlavní autoři: Paul, B. B., Jacobs, A. A., Strauss, R. R., Sbarra, A. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1970
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC416025/
https://ncbi.nlm.nih.gov/pubmed/16557854
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