Role of the Phagocyte in Host-Parasite Interactions XXIV. Aldehyde Generation by the Myeloperoxidase-H(2)O(2)-Chloride Antimicrobial System: a Possible In Vivo Mechanism of Action

Myeloperoxidase (MPO), H(2)O(2), and chloride ions in the presence of bacteria form aldehydes and are bactericidal. The use of heat-inactivated MPO prevented both killing and aldehyde generation. Decarboxylation and deamination of carboxyl and amino group substrates arising from the bacterial surfac...

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發表在:	Infect Immun
Principais autores:	Paul, B. B., Jacobs, A. A., Strauss, R. R., Sbarra, A. J.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1970
主題:	Antimicrobial Agents and Chemotherapy
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16557854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.2.4.414-418.1970
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