Role of the Phagocyte in Host-Parasite Interactions XXIV. Aldehyde Generation by the Myeloperoxidase-H(2)O(2)-Chloride Antimicrobial System: a Possible In Vivo Mechanism of Action
Myeloperoxidase (MPO), H(2)O(2), and chloride ions in the presence of bacteria form aldehydes and are bactericidal. The use of heat-inactivated MPO prevented both killing and aldehyde generation. Decarboxylation and deamination of carboxyl and amino group substrates arising from the bacterial surfac...
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| Publié dans: | Infect Immun |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1970
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16557854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.2.4.414-418.1970 |
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