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Identification of a new class of small molecules that efficiently reactivate latent Epstein-Barr virus

Epstein-Barr Virus (EBV) persists as a latent infection in many lymphoid and epithelial malignancies, including Burkitt's lymphomas, nasopharyngeal carcinomas, and gastric carcinomas. Current chemotherapeutic treatments of EBV-positive cancers include broad- spectrum cytotoxic drugs that ignore...

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Detalhes bibliográficos
Main Authors: Tikhmyanova, Nadezhda, Schultz, David C., Lee, Theresa, Salvino, Joseph M., Lieberman, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159771/
https://ncbi.nlm.nih.gov/pubmed/24028149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4006326
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