Exponential increases of RNA virus fitness during large population transmissions.

The great adaptability shown by RNA viruses is a consequence of their high mutation rates. Here we investigate the kinetics of virus fitness gains during repeated transfers of large virus populations in cell culture. Results always show that fitness increases exponentially. Low fitness clones exhibi...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Novella, I S, Duarte, E A, Elena, S F, Moya, A, Domingo, E, Holland, J J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597039/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.5841
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!