Evidence That the C-Terminal Domain of a Type B PutA Protein Contributes to Aldehyde Dehydrogenase Activity and Substrate Channeling

[Image: see text] Proline utilization A (PutA) is a bifunctional enzyme that catalyzes the oxidation of proline to glutamate. Structures of type A PutAs have revealed the catalytic core consisting of proline dehydrogenase (PRODH) and Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH) modules connect...

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Bibliographic Details
Main Authors: Luo, Min, Christgen, Shelbi, Sanyal, Nikhilesh, Arentson, Benjamin W., Becker, Donald F., Tanner, John J.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159212/
https://ncbi.nlm.nih.gov/pubmed/25137435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500693a
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