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Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site

Proline utilization A (PutA) proteins are bifunctional peripheral membrane flavoenzymes that catalyze the oxidation of l-proline to l-glutamate by the sequential activities of proline dehydrogenase and aldehyde dehydrogenase domains. Located at the inner membrane of Gram-negative bacteria, PutAs pla...

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Detalhes bibliográficos
Main Authors: Singh, Harkewal, Arentson, Benjamin W., Becker, Donald F., Tanner, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948300/
https://ncbi.nlm.nih.gov/pubmed/24550478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321621111
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