Genome-wide interaction studies reveal sex-specific asthma risk alleles

Asthma is a complex disease with sex-specific differences in prevalence. Candidate gene studies have suggested that genotype-by-sex interaction effects on asthma risk exist, but this has not yet been explored at a genome-wide level. We aimed to identify sex-specific asthma risk alleles by performing...

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Autors principals: Myers, Rachel A., Scott, Nicole M., Gauderman, W. James, Qiu, Weiliang, Mathias, Rasika A., Romieu, Isabelle, Levin, Albert M., Pino-Yanes, Maria, Graves, Penelope E., Villarreal, Albino Barraza, Beaty, Terri H., Carey, Vincent J., Croteau-Chonka, Damien C., del Rio Navarro, Blanca, Edlund, Christopher, Hernandez-Cadena, Leticia, Navarro-Olivos, Efrain, Padhukasahasram, Badri, Salam, Muhammad T., Torgerson, Dara G., Van den Berg, David J., Vora, Hita, Bleecker, Eugene R., Meyers, Deborah A., Williams, L. Keoki, Martinez, Fernando D., Burchard, Esteban G., Barnes, Kathleen C., Gilliland, Frank D., Weiss, Scott T., London, Stephanie J., Raby, Benjamin A., Ober, Carole, Nicolae, Dan L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Association Studies Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159149/
https://ncbi.nlm.nih.gov/pubmed/24824216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu222
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