Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

BACKGROUND: Allergic rhinitis is a common disease whose genetic basis is incompletely explained. We report an integrated genomic analysis of allergic rhinitis. METHODS: We performed genome wide association studies (GWAS) of allergic rhinitis in 5633 ethnically diverse North American subjects. Next,...

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Hauptverfasser: Bunyavanich, Supinda, Schadt, Eric E, Himes, Blanca E, Lasky-Su, Jessica, Qiu, Weiliang, Lazarus, Ross, Ziniti, John P, Cohain, Ariella, Linderman, Michael, Torgerson, Dara G, Eng, Celeste S, Pino-Yanes, Maria, Padhukasahasram, Badri, Yang, James J, Mathias, Rasika A, Beaty, Terri H, Li, Xingnan, Graves, Penelope, Romieu, Isabelle, Navarro, Blanca del Rio, Salam, M Towhid, Vora, Hita, Nicolae, Dan L, Ober, Carole, Martinez, Fernando D, Bleecker, Eugene R, Meyers, Deborah A, Gauderman, W James, Gilliland, Frank, Burchard, Esteban G, Barnes, Kathleen C, Williams, L Keoki, London, Stephanie J, Zhang, Bin, Raby, Benjamin A, Weiss, Scott T
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127082/
https://ncbi.nlm.nih.gov/pubmed/25085501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-48
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