Genome-wide interaction studies reveal sex-specific asthma risk alleles

Asthma is a complex disease with sex-specific differences in prevalence. Candidate gene studies have suggested that genotype-by-sex interaction effects on asthma risk exist, but this has not yet been explored at a genome-wide level. We aimed to identify sex-specific asthma risk alleles by performing...

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Hauptverfasser: Myers, Rachel A., Scott, Nicole M., Gauderman, W. James, Qiu, Weiliang, Mathias, Rasika A., Romieu, Isabelle, Levin, Albert M., Pino-Yanes, Maria, Graves, Penelope E., Villarreal, Albino Barraza, Beaty, Terri H., Carey, Vincent J., Croteau-Chonka, Damien C., del Rio Navarro, Blanca, Edlund, Christopher, Hernandez-Cadena, Leticia, Navarro-Olivos, Efrain, Padhukasahasram, Badri, Salam, Muhammad T., Torgerson, Dara G., Van den Berg, David J., Vora, Hita, Bleecker, Eugene R., Meyers, Deborah A., Williams, L. Keoki, Martinez, Fernando D., Burchard, Esteban G., Barnes, Kathleen C., Gilliland, Frank D., Weiss, Scott T., London, Stephanie J., Raby, Benjamin A., Ober, Carole, Nicolae, Dan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Association Studies Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159149/
https://ncbi.nlm.nih.gov/pubmed/24824216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu222
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