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Evidence that TMEM67 causes polycystic kidney disease through activation of JNK/ERK-dependent pathways
TMEM67 mutations are associated with severe autosomal recessive polycystic kidney disease (ARPKD) in both humans and animals. However, the molecular mechanisms underlying the pathogenesis of PKD caused by TMEM67 mutations remain to be determined. We have investigated the possible signaling pathways...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159072/ https://ncbi.nlm.nih.gov/pubmed/23456819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbin.10081 |
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