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The ERK and JNK pathways in the regulation of metabolic reprogramming

Most tumor cells reprogram their glucose metabolism as a result of mutations in oncogenes and tumor suppressors, leading to the constitutive activation of signaling pathways involved in cell growth. This metabolic reprogramming, known as aerobic glycolysis or the Warburg effect, allows tumor cells t...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Papa, Salvatore, Choy, Pui Man, Bubici, Concetta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398583/
https://ncbi.nlm.nih.gov/pubmed/30487597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0582-8
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