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Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126
GPR126 is an orphan heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptor (GPCR) that is essential for the development of diverse organs. We found that type IV collagen, a major constituent of the basement membrane, binds to Gpr126 and activates its signaling function. Type...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159047/ https://ncbi.nlm.nih.gov/pubmed/25118328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005347 |
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