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Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma

Germline mutations in the bone morphogenetic protein type II receptor (BMPRII) gene play an essential role in the pathogenesis of familial pulmonary arterial hypertension (FPAH). In view of the histological similarities between scleroderma (SSc) and FPAH arterial lesion, we examined the expression l...

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Autors principals: Wang, Yongqing, Kahaleh, Bashar
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159013/
https://ncbi.nlm.nih.gov/pubmed/23859708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12105
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