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Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma

Germline mutations in the bone morphogenetic protein type II receptor (BMPRII) gene play an essential role in the pathogenesis of familial pulmonary arterial hypertension (FPAH). In view of the histological similarities between scleroderma (SSc) and FPAH arterial lesion, we examined the expression l...

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Detalhes bibliográficos
Main Authors: Wang, Yongqing, Kahaleh, Bashar
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159013/
https://ncbi.nlm.nih.gov/pubmed/23859708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12105
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