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Selective enrichment of damaged DNA molecules for ancient genome sequencing
Contamination by present-day human and microbial DNA is one of the major hindrances for large-scale genomic studies using ancient biological material. We describe a new molecular method, U selection, which exploits one of the most distinctive features of ancient DNA—the presence of deoxyuracils—for...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158764/ https://ncbi.nlm.nih.gov/pubmed/25081630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.174201.114 |
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