Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries

Most ancient specimens contain very low levels of endogenous DNA, precluding the shotgun sequencing of many interesting samples because of cost. Ancient DNA (aDNA) libraries often contain <1% endogenous DNA, with the majority of sequencing capacity taken up by environmental DNA. Here we present a...

Full description

Saved in:
Bibliographic Details
Main Authors: Carpenter, Meredith L., Buenrostro, Jason D., Valdiosera, Cristina, Schroeder, Hannes, Allentoft, Morten E., Sikora, Martin, Rasmussen, Morten, Gravel, Simon, Guillén, Sonia, Nekhrizov, Georgi, Leshtakov, Krasimir, Dimitrova, Diana, Theodossiev, Nikola, Pettener, Davide, Luiselli, Donata, Sandoval, Karla, Moreno-Estrada, Andrés, Li, Yingrui, Wang, Jun, Gilbert, M. Thomas P., Willerslev, Eske, Greenleaf, William J., Bustamante, Carlos D.
Format: Artigo
Language:Inglês
Published: Elsevier 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824117/
https://ncbi.nlm.nih.gov/pubmed/24568772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.10.002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items