Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries

Most ancient specimens contain very low levels of endogenous DNA, precluding the shotgun sequencing of many interesting samples because of cost. Ancient DNA (aDNA) libraries often contain <1% endogenous DNA, with the majority of sequencing capacity taken up by environmental DNA. Here we present a...

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主要な著者: Carpenter, Meredith L., Buenrostro, Jason D., Valdiosera, Cristina, Schroeder, Hannes, Allentoft, Morten E., Sikora, Martin, Rasmussen, Morten, Gravel, Simon, Guillén, Sonia, Nekhrizov, Georgi, Leshtakov, Krasimir, Dimitrova, Diana, Theodossiev, Nikola, Pettener, Davide, Luiselli, Donata, Sandoval, Karla, Moreno-Estrada, Andrés, Li, Yingrui, Wang, Jun, Gilbert, M. Thomas P., Willerslev, Eske, Greenleaf, William J., Bustamante, Carlos D.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2013
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824117/
https://ncbi.nlm.nih.gov/pubmed/24568772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.10.002
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