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Improving access to endogenous DNA in ancient bones and teeth

Poor DNA preservation is the most limiting factor in ancient genomic research. In the majority of ancient bones and teeth, endogenous DNA molecules represent a minor fraction of the whole DNA extract, rendering shot-gun sequencing inefficient for obtaining genomic data. Based on ancient human bone s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Damgaard, Peter B., Margaryan, Ashot, Schroeder, Hannes, Orlando, Ludovic, Willerslev, Eske, Allentoft, Morten E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472031/
https://ncbi.nlm.nih.gov/pubmed/26081994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11184
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