Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

Microbiota regulate intestinal physiology by modifying host gene expression along the length of the intestine, but the underlying regulatory mechanisms remain unresolved. Transcriptional specificity occurs through interactions between transcription factors (TFs) and cis-regulatory regions (CRRs) cha...

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Autors principals: Camp, J. Gray, Frank, Christopher L., Lickwar, Colin R., Guturu, Harendra, Rube, Tomas, Wenger, Aaron M., Chen, Jenny, Bejerano, Gill, Crawford, Gregory E., Rawls, John F.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158762/
https://ncbi.nlm.nih.gov/pubmed/24963153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.165845.113
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