Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

Microbiota regulate intestinal physiology by modifying host gene expression along the length of the intestine, but the underlying regulatory mechanisms remain unresolved. Transcriptional specificity occurs through interactions between transcription factors (TFs) and cis-regulatory regions (CRRs) cha...

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Библиографические подробности
Главные авторы: Camp, J. Gray, Frank, Christopher L., Lickwar, Colin R., Guturu, Harendra, Rube, Tomas, Wenger, Aaron M., Chen, Jenny, Bejerano, Gill, Crawford, Gregory E., Rawls, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2014
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158762/
https://ncbi.nlm.nih.gov/pubmed/24963153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.165845.113
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