High resolution mapping of modified DNA nucleobases using excision repair enzymes

The incorporation and creation of modified nucleobases in DNA have profound effects on genome function. We describe methods for mapping positions and local content of modified DNA nucleobases in genomic DNA. We combined in vitro nucleobase excision with massively parallel DNA sequencing (Excision-se...

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Detalhes bibliográficos
Main Authors: Bryan, D. Suzi, Ransom, Monica, Adane, Biniam, York, Kerri, Hesselberth, Jay R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158761/
https://ncbi.nlm.nih.gov/pubmed/25015380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.174052.114
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