Nemo-like kinase is critical for p53 stabilization and function in response to DNA damage

The DNA damage response (DDR) acts as a protective mechanism for maintaining cell homeostasis. Nemo-like kinase (NLK) is a serine/threonine-protein kinase that has an important role in many pathways; however, its function in the DDR has not yet been defined. In our study, NLK-deficient HCT116 cells...

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Bibliographic Details
Main Authors: Zhang, H-H, Li, S-Z, Zhang, Z-Y, Hu, X-M, Hou, P-N, Gao, L, Du, R-L, Zhang, X-D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158690/
https://ncbi.nlm.nih.gov/pubmed/24926618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.78
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