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Structure of the periplasmic adaptor protein from a major facilitator superfamily (MFS) multidrug efflux pump

Periplasmic adaptor proteins are key components of bacterial tripartite efflux pumps. The 2.85 Å resolution structure of an MFS (major facilitator superfamily) pump adaptor, Aquifex aeolicus EmrA, shows linearly arranged α-helical coiled-coil, lipoyl, and β-barrel domains, but lacks the fourth membr...

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Détails bibliographiques
Auteurs principaux: Hinchliffe, Philip, Greene, Nicholas P., Paterson, Neil G., Crow, Allister, Hughes, Colin, Koronakis, Vassilis
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158417/
https://ncbi.nlm.nih.gov/pubmed/24996185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.06.055
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