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A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps
Bacteria such as Escherichia coli and Pseudomonas aeruginosa expel antibiotics and other inhibitors via tripartite multidrug efflux pumps spanning the inner and outer membranes and the intervening periplasmic space. A key event in pump assembly is the recruitment of an outer membrane-anchored TolC e...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838649/ https://ncbi.nlm.nih.gov/pubmed/17360572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610160104 |
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