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Structure of the periplasmic component of a bacterial drug efflux pump

Multidrug resistance among Gram-negative bacteria is conferred by three-component membrane pumps that expel diverse antibiotics from the cell. These efflux pumps consist of an inner membrane transporter such as the AcrB proton antiporter, an outer membrane exit duct of the TolC family, and a peripla...

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Bibliografiske detaljer
Main Authors: Higgins, Matthew K., Bokma, Evert, Koronakis, Eva, Hughes, Colin, Koronakis, Vassilis
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC454203/
https://ncbi.nlm.nih.gov/pubmed/15226509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400375101
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