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Using Galaxy-P to leverage RNA-Seq for the discovery of novel protein variations

BACKGROUND: Current practice in mass spectrometry (MS)-based proteomics is to identify peptides by comparison of experimental mass spectra with theoretical mass spectra derived from a reference protein database; however, this strategy necessarily fails to detect peptide and protein sequences that ar...

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Bibliografiske detaljer
Main Authors: Sheynkman, Gloria M, Johnson, James E, Jagtap, Pratik D, Shortreed, Michael R, Onsongo, Getiria, Frey, Brian L, Griffin, Timothy J, Smith, Lloyd M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158061/
https://ncbi.nlm.nih.gov/pubmed/25149441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-703
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