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Human Proteomic Variation Revealed by Combining RNA-Seq Proteogenomics and Global Post-Translational Modification (G-PTM) Search Strategy

[Image: see text] Mass-spectrometry-based proteomic analysis underestimates proteomic variation due to the absence of variant peptides and posttranslational modifications (PTMs) from standard protein databases. Each individual carries thousands of missense mutations that lead to single amino acid va...

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Pubblicato in:J Proteome Res
Autori principali: Cesnik, Anthony J., Shortreed, Michael R., Sheynkman, Gloria M., Frey, Brian L., Smith, Lloyd M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779408/
https://ncbi.nlm.nih.gov/pubmed/26704769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00817
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