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Human Proteomic Variation Revealed by Combining RNA-Seq Proteogenomics and Global Post-Translational Modification (G-PTM) Search Strategy

[Image: see text] Mass-spectrometry-based proteomic analysis underestimates proteomic variation due to the absence of variant peptides and posttranslational modifications (PTMs) from standard protein databases. Each individual carries thousands of missense mutations that lead to single amino acid va...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Cesnik, Anthony J., Shortreed, Michael R., Sheynkman, Gloria M., Frey, Brian L., Smith, Lloyd M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779408/
https://ncbi.nlm.nih.gov/pubmed/26704769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00817
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