Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements

B cells produce a diverse antibody repertoire by undergoing gene rearrangements. Pathogen exposure induces the clonal expansion of B cells expressing antibodies that can bind the infectious agent. To assess human B cell responses to trivalent seasonal influenza and monovalent pandemic H1N1 vaccinati...

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Main Authors: Jackson, Katherine J.L., Liu, Yi, Roskin, Krishna M., Glanville, Jacob, Hoh, Ramona A., Seo, Katie, Marshall, Eleanor L., Gurley, Thaddeus C., Moody, M. Anthony, Haynes, Barton F., Walter, Emmanuel B., Liao, Hua-Xin, Albrecht, Randy A., García-Sastre, Adolfo, Chaparro-Riggers, Javier, Rajpal, Arvind, Pons, Jaume, Simen, Birgitte B., Hanczaruk, Bozena, Dekker, Cornelia L., Laserson, Jonathan, Koller, Daphne, Davis, Mark M., Fire, Andrew Z., Boyd, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158033/
https://ncbi.nlm.nih.gov/pubmed/24981332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.05.013
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