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Modularized Functions of the Fanconi Anemia Core Complex
The Fanconi Anemia (FA) core complex provides the essential E3 ligase function for the FA pathway activation through the spatially defined FANCD2 ubiquitination. Of the seven FA gene products forming the core complex, FANCL possesses a RING domain with demonstrated E3 ligase activity. The other six...
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Hoofdauteurs: | , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2014
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157997/ https://ncbi.nlm.nih.gov/pubmed/24910428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.029 |
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