Integrase-Specific Enhancement and Suppression of Retroviral DNA Integration by Compacted Chromatin Structure In Vitro

Integration of viral DNA into the host chromosome is an obligatory step in retroviral replication and is dependent on the activity of the viral enzyme integrase. To examine the influence of chromatin structure on retroviral DNA integration in vitro, we used a model target comprising a 13-nucleosome...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Taganov, Konstantin D., Cuesta, Isabel, Daniel, René, Cirillo, Lisa Ann, Katz, Richard A., Zaret, Kenneth S., Skalka, Anna Marie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15140982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.11.5848-5855.2004
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