Integrase-Specific Enhancement and Suppression of Retroviral DNA Integration by Compacted Chromatin Structure In Vitro

Integration of viral DNA into the host chromosome is an obligatory step in retroviral replication and is dependent on the activity of the viral enzyme integrase. To examine the influence of chromatin structure on retroviral DNA integration in vitro, we used a model target comprising a 13-nucleosome...

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Bibliografiska uppgifter

I publikationen:	J Virol
Huvudupphov:	Taganov, Konstantin D., Cuesta, Isabel, Daniel, René, Cirillo, Lisa Ann, Katz, Richard A., Zaret, Kenneth S., Skalka, Anna Marie
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 2004
Ämnen:	Replication
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15140982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.11.5848-5855.2004
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