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Poly(Ethylene Glycol)-Cholesterol Inhibits L-Type Ca(2+) Channel Currents and Augments Voltage-Dependent Inactivation in A7r5 Cells

Cholesterol distributes at a high density in the membrane lipid raft and modulates ion channel currents. Poly(ethylene glycol) cholesteryl ether (PEG-cholesterol) is a nonionic amphipathic lipid consisting of lipophilic cholesterol and covalently bound hydrophilic PEG. PEG-cholesterol is used to for...

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Detalhes bibliográficos
Main Authors: Ochi, Rikuo, Chettimada, Sukrutha, Gupte, Sachin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157810/
https://ncbi.nlm.nih.gov/pubmed/25197984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107049
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