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Matrix Expansion and Syncytial Aggregation of Syndecan-1(+) Cells Underpin Villous Atrophy in Coeliac Disease

BACKGROUND: We studied the expression of sulphated glycosaminoglycans (GAGs) in coeliac disease (CD) mucosa, as they are critical determinants of tissue volume, which increases in active disease. We also examined mucosal expression of IL-6, which stimulates excess GAG synthesis in disorders such as...

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Detalhes bibliográficos
Main Authors: Salvestrini, Camilla, Lucas, Mark, Lionetti, Paolo, Torrente, Franco, James, Sean, Phillips, Alan D., Murch, Simon H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157760/
https://ncbi.nlm.nih.gov/pubmed/25198673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106005
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