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Matrix Expansion and Syncytial Aggregation of Syndecan-1(+) Cells Underpin Villous Atrophy in Coeliac Disease

BACKGROUND: We studied the expression of sulphated glycosaminoglycans (GAGs) in coeliac disease (CD) mucosa, as they are critical determinants of tissue volume, which increases in active disease. We also examined mucosal expression of IL-6, which stimulates excess GAG synthesis in disorders such as...

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Main Authors: Salvestrini, Camilla, Lucas, Mark, Lionetti, Paolo, Torrente, Franco, James, Sean, Phillips, Alan D., Murch, Simon H.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157760/
https://ncbi.nlm.nih.gov/pubmed/25198673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106005
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