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Genome-Wide Binding and Transcriptome Analysis of Human Farnesoid X Receptor in Primary Human Hepatocytes

BACKGROUND & AIMS: Farnesoid X receptor (FXR, NR1H4) is a ligand-activated transcription factor, belonging to the nuclear receptor superfamily. FXR is highly expressed in the liver and is essential in regulating bile acid homeostasis. FXR deficiency is implicated in numerous liver diseases and m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhan, Le, Liu, Hui-Xin, Fang, Yaping, Kong, Bo, He, Yuqi, Zhong, Xiao-bo, Fang, Jianwen, Wan, Yu-Jui Yvonne, Guo, Grace L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157742/
https://ncbi.nlm.nih.gov/pubmed/25198545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105930
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