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Hepatocyte Nuclear Factor 4 Alpha and Farnesoid X Receptor Co-regulates Gene Transcription in Mouse Livers on a Genome-wide Scale
PURPOSE: Farnesoid X receptor (Fxr) is a ligand-activated nuclear receptor critical for liver function. Reports indicate that functions of Fxr in the liver may overlap with those of hepatocyte nuclear factor 4α (Hnf4α), but studies of their precise genome-wide interaction to regulate gene transcript...
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Autores principales: | , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711942/ https://ncbi.nlm.nih.gov/pubmed/23462932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1006-7 |
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