A Bioengineered Hydrogel System Enables Targeted and Sustained Intramyocardial Delivery of Neuregulin, Activating the Cardiomyocyte Cell Cycle and Enhancing Ventricular Function in a Murine Model of Ischemic Cardiomyopathy

BACKGROUND: Neuregulin (NRG) is a member of the epidermal growth factor family possessing a critical role in cardiomyocyte development and proliferation. Systemic administration of NRG demonstrated efficacy in cardiomyopathy animal models, leading to clinical trials employing daily NRG infusions. Th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cohen, Jeffrey E., Purcell, Brendan P., MacArthur, John W., Mu, Anbin, Shudo, Yasuhiro, Patel, Jay B., Brusalis, Christopher M., Trubelja, Alen, Fairman, Alexander S., Edwards, Bryan B., Davis, Mollie S., Hung, George, Hiesinger, William, Atluri, Pavan, Margulies, Kenneth B., Burdick, Jason A., Woo, Y. Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157671/
https://ncbi.nlm.nih.gov/pubmed/24902740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.113.001273
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados