Sustained Release of Engineered Stromal Cell–Derived Factor 1-α From Injectable Hydrogels Effectively Recruits Endothelial Progenitor Cells and Preserves Ventricular Function After Myocardial Infarction

BACKGROUND: Exogenously delivered chemokines have enabled neovasculogenic myocardial repair in models of ischemic cardiomyopathy; however, these molecules have short half-lives in vivo. In this study, we hypothesized that the sustained delivery of a synthetic analog of stromal cell–derived factor 1-...

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Detalhes bibliográficos
Main Authors: MacArthur, John W., Purcell, Brendan P., Shudo, Yasuhiro, Cohen, Jeffrey E., Fairman, Alex, Trubelja, Alen, Patel, Jay, Hsiao, Philip, Yang, Elaine, Lloyd, Kelsey, Hiesinger, William, Atluri, Pavan, Burdick, Jason A., Woo, Y. Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111255/
https://ncbi.nlm.nih.gov/pubmed/24030424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.000343
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