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Injectable shear-thinning hydrogels to deliver endothelial progenitor cells, enhance cell engraftment, and improve ischemic myocardium

OBJECTIVES: The clinical translation of cell based therapies for ischemic heart disease has been limited due to low cell retention (<1%) within and poor targeting to ischemic myocardium. To address these issues, we developed an injectable shear-thinning hyaluronic acid hydrogel (STG) and endothel...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Gaffey, Ann C., Chen, Minna H., Venkataraman, Chantel M., Trubelja, Alen, Rodell, Christopher B., Dinh, Patrick V., Hung, George, MacArthur, John W., Soopan, Renganaden V., Burdick, Jason A., Atluri, Pavan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637242/
https://ncbi.nlm.nih.gov/pubmed/26293548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2015.07.035
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