Delivery of progenitor cells with injectable shear-thinning hydrogel maintains geometry and normalizes strain to stabilize cardiac function after ischemia

OBJECTIVES: The ventricle undergoes adverse remodeling after myocardial infarction, resulting in abnormal biomechanics and decreased function. We hypothesize that tissue-engineered therapy could minimize postischemic remodeling through mechanical stress reduction and retention of tensile myocardial...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Gaffey, Ann C., Chen, Minna H., Trubelja, Alen, Venkataraman, Chantel M., Chen, Carol W., Chung, Jennifer J., Schultz, Susan, Sehgal, Chandra M., Burdick, Jason A., Atluri, Pavan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769598/
https://ncbi.nlm.nih.gov/pubmed/30579534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2018.07.117
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