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A New Reactivity Mode of Diazo-Group: Diastereoselective 1,3-Aminoalkylation Reaction of β-Amino-α-Diazoesters Towards Triazolines()

A novel reactivity mode of a diazo-group, the 1,3-addition of a nucleophile and an electrophile to the diazo-group, has been realized in the intramolecular aminoalkylation of β-amino-α-diazoesters to form tetrasubstituted 1,2,3-triazolines. The reaction proved to have a broad scope, good functional...

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Detalhes bibliográficos
Main Authors: Kuznetsov, Alexey, Gulevich, Anton V., Wink, Donald J., Gevorgyan, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157640/
https://ncbi.nlm.nih.gov/pubmed/24986811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404352
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