Elevated levels of glycosylphosphatidylinositol (GPI) anchored proteins in plasma from human cancers detected by C. septicum alpha toxin

The glycosylphosphatidylinositol (GPI) anchor is a glycan and lipid posttranslational modification added to proteins in the endoplasmic reticulum. Certain enzymes within the GPI biosynthetic pathway, particularly the subunits of the GPI transamidase, are elevated in various human cancers. Specific G...

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Hauptverfasser: Dolezal, Samuel, Hester, Shanterian, Kirby, Pamela S., Nairn, Allison, Pierce, Michael, Abbott, Karen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157464/
https://ncbi.nlm.nih.gov/pubmed/24643042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CBM-130377
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