Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum α-toxin

Aerolysin of the Gram-negative bacterium Aeromonas hydrophila consists of small (SL) and large (LL) lobes. The α-toxin of Gram-positive Clostridium septicum has a single lobe homologous to LL. These toxins bind to glycosylphosphatidylinositol (GPI)-anchored proteins and generate pores in the cell’s...

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Main Authors: Hong, Yeongjin, Ohishi, Kazuhito, Inoue, Norimitsu, Kang, Ji Young, Shime, Hiroaki, Horiguchi, Yasuhiko, van der Goot, F.Gisou, Sugimoto, Nakaba, Kinoshita, Taroh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129030/
https://ncbi.nlm.nih.gov/pubmed/12356721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf508
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