Elevated levels of glycosylphosphatidylinositol (GPI) anchored proteins in plasma from human cancers detected by C. septicum alpha toxin

The glycosylphosphatidylinositol (GPI) anchor is a glycan and lipid posttranslational modification added to proteins in the endoplasmic reticulum. Certain enzymes within the GPI biosynthetic pathway, particularly the subunits of the GPI transamidase, are elevated in various human cancers. Specific G...

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Autores principales: Dolezal, Samuel, Hester, Shanterian, Kirby, Pamela S., Nairn, Allison, Pierce, Michael, Abbott, Karen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157464/
https://ncbi.nlm.nih.gov/pubmed/24643042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CBM-130377
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