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Deformable elastic network refinement for low-resolution macromolecular crystallography

Crystals of membrane proteins and protein complexes often diffract to low resolution owing to their intrinsic molecular flexibility, heterogeneity or the mosaic spread of micro-domains. At low resolution, the building and refinement of atomic models is a more challenging task. The deformable elastic...

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Détails bibliographiques
Auteurs principaux: Schröder, Gunnar F., Levitt, Michael, Brunger, Axel T.
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157441/
https://ncbi.nlm.nih.gov/pubmed/25195739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714016496
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