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Improving the accuracy of macromolecular structure refinement at 7 Å resolution

In X-ray crystallography, molecular replacement and subsequent refinement is challenging at low resolution. We compared refinement methods using synchrotron diffraction data of photosystem I at 7.4 Å resolution, starting from different initial models with increasing deviations from the known high-re...

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Detalhes bibliográficos
Main Authors: Brunger, Axel T., Adams, Paul D., Fromme, Petra, Fromme, Raimund, Levitt, Michael, Schröder, Gunnar F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380535/
https://ncbi.nlm.nih.gov/pubmed/22681901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.04.020
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